My name is Alex. I have 6 years of experience in resolving QuickBooks queries and errors. There are several reasons that your QuickBooks won't open the printer setup. The QuickBooks desktop application might have restricted folder access permission. The printer is outdated or not compatible with your computer. check whether the printer windows spooler services are paused. Lastly, your antivirus program might be interrupting access to the printer setup. Thus, you can change these settings or connect with a technician.